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HLA system

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HLA system
n
(Life Sciences & Allied Applications / Biochemistry) human leucocyte antigen system; a group of the most important antigens responsible for tissue compatibility, together with the genes that encode them. For tissue and organ transplantation to be successful there needs to be a minimum number of HLA differences between the donor's and recipient's tissue


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Dausset's discovery in 1958 of the HLA system allowed physicians to verify compatibility between the donor and recipient of an organ to be transplanted.
the role of the HLA system in distinguishing self from non-self, and in eliminating diseased cells, and how this presents important biomarkers for diagnosis and therapy.
 
 
 
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