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HMG-CoA reductase

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Noun1.HMG-CoA reductase - a liver enzyme that is responsible for producing cholesterol
reductase - an enzyme that catalyses the biochemical reduction of some specified substance


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Inhibition of HMG-CoA reductase by statin results in decreased synthesis of cholesterol and other products downstream of mevalonate, which may produce adverse effects in statin therapy.
They have thus far found that in these yeast, the regulatory protein Insig also regulates HMG-CoA reductase but does it differently.
 
 
 
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