Hand-Schuller-Christian disease

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Noun1.Hand-Schuller-Christian disease - inflammatory histiocytosis associated with disturbance of cholesterol metabolism; occurs chiefly in young children and is characterized by cystic defects of the skull and diabetes insipidus
histiocytosis - a blood disease characterized by an abnormal multiplication of macrophages
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The screen door flew open as his father pushed at it with one hand, Alfred launching himself across the short lawn at his target.