China says yes, with more than 15 million cases of hand, foot, and mouth disease
resulting in 3,500 deaths since surveillance started in 2009," Heli Harvala, MD, said at the annual meeting of the European Society for Paediatric Infectious Diseases.
Now in clinical trials, investigational bivalent vaccines are directed against other EV-A71 subgeno types in addition to C-4, and also against another enterovirus, coxsackievirus serotype A16, the most common cause of classic hand, foot, and mouth disease
in the United States.
The past few months have seen multiple outbreaks of hand, foot, and mouth disease
on college campuses throughout the United States.
However, the clinical signs, including the unique morphology and distribution of grouped vesicles and papules was suggestive of hand, foot, and mouth disease
(HFMD), although the patient did not have oral lesions and reported no contact with another person with HFMD.
Although CAV6 is commonly associated with hand, foot, and mouth disease
(HFMD) and herpangina (1,2), it has not been of concern until the recent global outbreaks of HFMD (3-6).
According to the Vietnamese MoH, there were approximately 116,418 people in 63 provinces confirmed to have hand, foot, and mouth disease
(HFMD) from January 1 to October 7.
Identification and validation of clinical predictors for the risk of neurological involvement in children with hand, foot, and mouth disease
Chinese biopharmaceutical company Sinovac Biotech Ltd (NASDAQ: SVA) declared on Wednesday that the unblinded results of its Phase I clinical trial for its proprietary inactivated vaccine against human enterovirus 71 (EV71), which causes Hand, Foot, and Mouth Disease
(HFMD), reported positive safety and tolerance profiles, as well as good immune responses induced by the vaccine candidates.
AMEX:SVA), Beijing, a leading developer and provider of vaccines in China, has initiated development of a vaccine human enterovirus 71, EV 71, which causes hand, foot, and mouth disease
In addition, although it poses an economic threat to livestock producers, it does not pose a health risk to humans (and is distinct from the hand, foot, and mouth disease
recently prevalent in Malaysia).
Hand, foot, and mouth disease
(HFMD) is a common illness of infants and children.
Enterovirus was detected in specimens from the woman and child by reverse transcriptase-polymerase chain reaction (RT-PCR) testing performed at MDH; partial genome sequencing by CDC showed that both patients were infected with coxsackievirus A6 (CVA6), one of the members of the genus Enterovirus that causes hand, foot, and mouth disease