HapMap


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Hap·Map

 (hăp′măp′)
n.
A database of common genetic variants in human beings from various regions of the world, the result of an international project to describe patterns of genetic variation and their relation to various diseases.

[haplo(type) map.]
References in periodicals archive ?
We report an integrated validation strategy using HapMap samples and samples with specific disease variants for a combined targeted NGS panel for 5 diseases, including early infantile epileptic encephalopathy, craniofacial disorders, RASopathy disorders, hearing loss, and hereditary cancer.
The Chinese Han population's SNP data of SIRT6 gene (8,427 bp, 8 exons) plus 3 kb upstream and downstream was obtained in the HapMap data release 27 (http://www.
Furthermore, the purpose of the study was to determine the inter-ethnic variability of allele frequencies of the above genes among the south Indians with the HapMap and other populations from previously published reports.
We first selected tag SNPs from the International HapMap Project (HMP 2009) and SeattleSNPs Genome Variation Server (GVS 2013) using the [r.
Data set 1 included: genotype data for 5238 CNV loci generated by testing 450 HapMap samples at 500-bp resolution (2).
With the goal towards excellence, high efficiency and accuracy, BGI has a large number of accomplishments, including sequencing 1 percent of the human genome for the international Human Genome Project, contributing 10 pe rcent of International Human HapMap Project, carrying out research to combat SARS and the E.
1,2) Since then, we have seen additional massive investment by the public sector to determine the function of this complex blueprint for life, including the International HapMap project to map the inherited blocks of the genome across global populations, and the Encyclopedia of DNA Elements (ENCODE) project to define the "functional elements" within the genome.
Quite a few of our staff scientists once participated in the International HapMap Project too.
These studies were made possible by tools developed through the Human Genome Project, which mapped human genes, and related projects, such the International HapMap Project, which identified common patterns of genetic variation within the human genome.
In the first phase, we selected a minimal set of tagging SNPs within each candidate gene using the HapMap Genome Browser and Haploview software.
The HapMap project (The international HapMap Consortium, 2005) has demonstrated that the underlying LD structure of the human genome can be defined in terms of discrete blocks (coldspots; low recombination regions) separated by hotspots (high recombination regions).