heat shock protein

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Related to Heat-shock protein: heat shock response, Hsp90

heat shock protein

n.
Any of a group of cellular proteins produced under physiological stress, such as high or low body temperature, that stabilize other cellular proteins and adjust cellular metabolism to cope with the stress.
References in periodicals archive ?
Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology.
The bacterial heat-shock response is not limited to changes in temperature and is a general stress response, as many of the heat-shock proteins are induced by interaction with eukaryotic hosts (Van bogelen et al.
Antibodies to human heat-shock protein 60 are associated with the presence and severity of coronary artery disease: evidence for an autoimmune component of atherogenesis.
Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis.
The function of heat-shock proteins in stress tolerance, degradation and reactivation of damaged proteins.
Heat-shock protein 104 expression is sufficient for thermotolerance in yeast.
Some evidence shows that inflammation and subsequent tissue damage in chronic PID are due to an immunopathologic reaction against a chlamydial heat-shock protein (hsp60) (14).
Activation of HSF and selective increase in heat-shock proteins by acute dexamethas one treatment.
She found that the immune system in one strain of diabetic mice produced antibodies to their own heat-shock protein 60.
In our view, Antigenics is the pioneer and leader in providing individualized medicine through cancer vaccines based on its proprietary heat-shock protein (HSP) therapy," said Ginsberg.