helicase


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helicase

(ˈhiːlɪˌkeɪz)
n
any of a group of proteins that are vital to all living organisms
References in periodicals archive ?
In actual the NS3 protein of dengue virus is multifunctional enzyme, acting as protease and a helicase domain, in specific sites the protease is responsible for the survival of dengue virus.
RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial lung disease.
Peterson, Inhibition of Herpes Simplex Virus Replication by a 2-amino thiazole via Interactions with the Helicase Component of the UL5-UL8-UL52 Complex.
Pontin and reptin are the helicase ATPases associated with diverse cellular activities ([AAA.
A RecB-like helicase in Helicobacter pylori is important for DNA repair and host colonization.
Twinkle helicase (PEO1) gene mutation causes mitochondrial DNA depletion.
Activated at the G1/S phase transition, CDC7 activates the helicase that unwinds DNA in preparation for cellular DNA replication.
The N-terminal domain of NS3 is a serine protease, although its function requires interaction with the NS2B protein as a cofactor, (38-42) whereas the C-terminal domain of NS3 serves as both a helicase, which unwinds double-stranded RNA formed during viral genome replication, and a 50-RNA triphosphatase, which is involved in formation of the 50 RNA cap.
TDRD9 contains an ATPase/DExH-box ATPase (DExH)type helicase and a Tudor domain and functions in silencing LINE-1 retrotransposon during spermatogenesis.
The PI3K/mTOR signaling pathway controls the assembly of eIF4F, which of eIF4A is a specific component with helicase activity in regulating protein translation (Chu and Pelletier 2015).
Thermophilic helicase Not measured 2011 [39] dependent amplification (tHDA) assay: helicase unwinds double-stranded DNA at constant temperature.