helper T-cell


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helper T-cell

n
(Biochemistry) See T-lymphocyte
References in periodicals archive ?
T cells in the latter coexpress programmed death receptor-1 (PD-1), B-cell lymphoma 6 (BCL6), chemokine ligand 13 (CXCL13), and inducible T-cell costimulator (CD278), indicating a follicular helper T-cell phenotype.
The “T” in trauma: The helper T-cell response and the role of immunomodulation in trauma and burn patients.
Progesterone presence, which may suppress the maternal immune response and alter the balance between type-1 helper T-cell response and type-2 helper T-cell response.
Potential benefits include the control of acute retroviral symptoms, prevention of abnormal helper T-cell function and reduction in the pace of decline, delaying or preventing decreased immune function and vulnerability to opportunistic infections, decreasing the initial viral load set point, which may decrease transmission, limiting viral evolution and diversity, potential slowing of the rate of disease progression among patients with a genetic predisposition, and decrease in the size of the latent HIV pool.
Several vaccination strategies have been evaluated in mouse and ferret models, including M2-expressing recombinant viruses, M2 recombinant proteins (20,21), M2-encoding plasmid DNA (29), and synthetic M2e peptides that were chemically linked to carrier proteins or synthetically linked to defined helper T-cell determinants (22-24).
Antigen Express scientists have pioneered strategies for enhancing helper T-cell responses to DNA vaccines by controlling the function of the immunoregulatory Ii-protein.
Defining promiscuous MHC class II helper T-cell epitopes for the HER2/neu tumor antigen.
When the virus enters the body, it ravenously attacks an immune-system cell--a white blood cell called a helper T-cell (see "The Life Cycle of HIV").
What we're spending substantial effort on right now is trying to formulate it in order to induce immune responses to all areas of the immune system, meaning helper T-cell responses, cytotoxic T-cell responses, and antibody responses, and also eliciting consistent and high-level responses in the majority of patients.
HIV propagates by attacking a kind of immune cell known as a helper T-cell.
Goodkin suggests that the stability of helper T-cell counts among depressed HIV-positive men in Rabkin's study may reflect the absence of such controls.
The DNA vaccine is designed to induce a strong helper T-cell response, with the aim of enhancing induction of a cytotoxic T-cell response against tumor cells.