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According to the company, Ogivri , which is a biosimilar to Herceptin (trastuzumab), has been approved for all indications included in the label of the reference product, Herceptin, including for the treatment of HER2-overexpressing breast cancer and metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma).
REGISTERED NURSE and breast cancer drug campaigner and survivor Chris Walsh spoke about her two-year battle with Pharmac a decade ago, to fully fund herceptin.
Genentech scientists, having cloned the first human HER2 gene earlier, create Herceptin by humanizing a mouse antibody directed at HER2.
Roche/Genentech's Herceptin (trastuzumab), first approved in the US in 1998, and in the EU in 2000, is the gold-standard treatment for HER2-positive breast cancer, and is prescribed both for patients with early-stage and metastatic disease.
Roche today announced final survival results from the Phase III CLEOPATRA study, which showed that adding Perjeta (pertuzumab) to Herceptin (trastuzumab) and docetaxel chemotherapy extended the lives (overall survival; OS) of people with previously untreated HER2-positive metastatic breast cancer (mBC) by 15.
On Monday patients in the North East with HER2-positive breast cancer will begin to receive a new injection of the drug Herceptin, given just beneath the skin.
Patients currently receive the drug Herceptin via a drip, usually visiting hospital every three weeks.
Patients with this form of breast cancer can currently undergo a combined treatment of Herceptin and chemotherapy, if it is suitable for their type of cancer.
Women on combination treatment of pertuzumab alongside the 'wonder' drug Herceptin and chemotherapy lived on average for 18 months without their disease worsening, compared with 12 months for those not taking it.
USING chemotherapy and the drug Herceptin to treat early-stage breast cancer for women with an aggressive form of the disease could help boost survival rates, a study has found.
L IKE many other new cancer treatments, Herceptin was hailed as a miracle drug when it was first licensed a decade ago.
The companies will collaborate on the regulatory submissions of Dako's HercepTest and HER2 FISH pharmDx in the USA as companion diagnostics for Herceptin (trastuzumab) in patients with advanced HER2-positive stomach (gastric) cancer.
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