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homeobox

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
homeobox  (hm--bks)
Any of various DNA sequences containing about 180 nucleotides that encode for corresponding sequences of usually 60 amino acids, called homeodomains, found in proteins that bind DNA and regulate gene transcription. Genes containing homeoboxes are found in all eukaryotic genomes and are associated with cell differentiation and bodily segmentation during embryologic development.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.homeobox - one of various similar homeotic genes that are involved in bodily segmentation during embryonic development
homeobox gene
homeotic gene - one the genes that are involved in embryologic development


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We next matched genes in these three pathways with the 163 genes and identified 12 candidate genes: B-cell CLL/lymphoma 6 (BCL6), IL1[alpha] (ILIA), IL8, PTGS2, DTR, chemokine (C-X-C motif) ligand 3 (CXCL3), promyelocytic leukemia (PML), sine oculis homeobox homolog 1 (Drosophila) (SIX1), tumor necrosis factor (TNF), [alpha]-induced protein 3 (TNFAIP3), Zn finger and BTB domain containing 1 (ZBTB1), Zn finger protein 44 (KOX 7) (ZNF44), and Zn finger protein 450 (ZNF450).
Discrimination of vanadium from zinc using gene profiling in human ... by Huang, Yuh-Chin T. / Environmental Health Perspectives
161 Homeobox genes 20 Hominids 117, 179 Homo sapiens 149, 261 Homocysteine 100, 141 Honey 317 Hooper, David C.
Science news index. (Index) by Science News
Having identified the homeobox segment, researchers searched for it in other organisms.
Strands of Life by Bailey, Ronald / Reason
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