homeobox

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ho·me·o·box

 (hō′mē-ə-bŏks′)
n.
A short DNA sequence contained within all homeobox genes that codes for a specific amino acid sequence that binds to DNA and regulates transcription.

[homeo(tic gene) + box (from the fact that the DNA sequence is short and when written can be enclosed by a box on paper).]

homeobox

(ˈhɒmɪəʊˌbɒks)
n
(Genetics) genetics a particular sequence of DNA found in genes that regulate cell development
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.homeobox - one of various similar homeotic genes that are involved in bodily segmentation during embryonic development
homeotic gene - one the genes that are involved in embryologic development
References in periodicals archive ?
The opposing homeobox genes Goosecoid and Ventl/2 self-regulate Xenopus patterning.
This event may partially be regulated by the HHEX homeobox genes that regulate the proliferation of endoderm of the anterior intestine and the activation of the epithelium with respect to the cardiac mesoderm that produces FGF during development (23).
Homeobox genes are involved in body plan formation and in the regulation of many developmental processes in bilateria.
Deletions or rearrangements in the genome of two homeobox genes DLX5 and DLX6 are reported to be linked with SHFM-I.
Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis.
For example, vertebrate limbs can be lost by changes in expression of homeobox genes.
among others, thought that the answer to the genetic puzzle lay in the expression of a specific group of homeobox genes called Msx.
Possibility of teratogenic exposure with diazepam (9), diphenylhydantoin (3), genetic factors such as trisomy 18 (7), single gene defects in blastogenesis and mutations in homeobox genes such as HLXB9 (3) have been suggested.
We previously observed that a 4-day treatment with TCDD after the completion of EB formation deregulated the expression of > 50 homeobox genes, many by as much as 50- to 100-fold above or below the control (Wang et al.
Many homeobox genes are influenced by hormones such as estrogen.
Discovered first in 1983 by Ernst Hafen et al in the university of Basel, Switzerland, Homeobox genes are an evolutionary conserved class of transcription factors that are key regulators during developmental processes such as regional specifications, patterning and differentiation.