humanize(redirected from Humanized antibodies)
Also found in: Thesaurus, Medical, Legal, Wikipedia.
Related to Humanized antibodies: Chimeric Antibody
tr.v. hu·man·ized, hu·man·iz·ing, hu·man·iz·es
1. To portray or endow with human characteristics or attributes; make human: humanized the puppets with great skill.
2. To imbue with humaneness or human kindness; civilize: acts of courtesy that humanize life in a big city.
a. To modify (a nonhuman compound, cell, organ, or organism) such that some of its components are replaced with human forms of those components, usually by means of genetic engineering.
b. To replace most of the variable region of (a monoclonal antibody from a nonhuman source) with a human sequence of amino acids so that the resulting antibody is more compatible with the human immune system.
hu′man·i·za′tion (-mə-nĭ-zā′shən) n.
1. to make or become human
2. to make or become humane
ˌhumaniˈzation, ˌhumaniˈsation n
ˈhumanˌizer, ˈhumanˌiser n
hu•man•ize(ˈhyu məˌnaɪz; often ˈyu-)
v.t. -ized, -iz•ing. v.t.
1. to make humane, kind, or gentle; civilize.
2. to give or attribute human character to.
Past participle: humanized
Switch to new thesaurus
|Verb||1.||humanize - make more humane; "The mayor tried to humanize life in the big city"|
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"