humanize

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Related to Humanized antibodies: Chimeric Antibody

hu·man·ize

 (hyo͞o′mə-nīz′)
tr.v. hu·man·ized, hu·man·iz·ing, hu·man·iz·es
1. To portray or endow with human characteristics or attributes; make human: humanized the puppets with great skill.
2. To imbue with humaneness or human kindness; civilize: acts of courtesy that humanize life in a big city.
3.
a. To modify (a nonhuman compound, cell, organ, or organism) such that some of its components are replaced with human forms of those components, usually by means of genetic engineering.
b. To replace most of the variable region of (a monoclonal antibody from a nonhuman source) with a human sequence of amino acids so that the resulting antibody is more compatible with the human immune system.

hu′man·i·za′tion (-mə-nĭ-zā′shən) n.
hu′man·iz′er n.

humanize

(ˈhjuːməˌnaɪz) or

humanise

vb
1. to make or become human
2. to make or become humane
ˌhumaniˈzation, ˌhumaniˈsation n
ˈhumanˌizer, ˈhumanˌiser n

hu•man•ize

(ˈhyu məˌnaɪz; often ˈyu-)

v.t. -ized, -iz•ing. v.t.
1. to make humane, kind, or gentle; civilize.
2. to give or attribute human character to.
[1595–1605]
hu′man•iz`er, n.

humanize


Past participle: humanized
Gerund: humanizing

Imperative
humanize
humanize
Present
I humanize
you humanize
he/she/it humanizes
we humanize
you humanize
they humanize
Preterite
I humanized
you humanized
he/she/it humanized
we humanized
you humanized
they humanized
Present Continuous
I am humanizing
you are humanizing
he/she/it is humanizing
we are humanizing
you are humanizing
they are humanizing
Present Perfect
I have humanized
you have humanized
he/she/it has humanized
we have humanized
you have humanized
they have humanized
Past Continuous
I was humanizing
you were humanizing
he/she/it was humanizing
we were humanizing
you were humanizing
they were humanizing
Past Perfect
I had humanized
you had humanized
he/she/it had humanized
we had humanized
you had humanized
they had humanized
Future
I will humanize
you will humanize
he/she/it will humanize
we will humanize
you will humanize
they will humanize
Future Perfect
I will have humanized
you will have humanized
he/she/it will have humanized
we will have humanized
you will have humanized
they will have humanized
Future Continuous
I will be humanizing
you will be humanizing
he/she/it will be humanizing
we will be humanizing
you will be humanizing
they will be humanizing
Present Perfect Continuous
I have been humanizing
you have been humanizing
he/she/it has been humanizing
we have been humanizing
you have been humanizing
they have been humanizing
Future Perfect Continuous
I will have been humanizing
you will have been humanizing
he/she/it will have been humanizing
we will have been humanizing
you will have been humanizing
they will have been humanizing
Past Perfect Continuous
I had been humanizing
you had been humanizing
he/she/it had been humanizing
we had been humanizing
you had been humanizing
they had been humanizing
Conditional
I would humanize
you would humanize
he/she/it would humanize
we would humanize
you would humanize
they would humanize
Past Conditional
I would have humanized
you would have humanized
he/she/it would have humanized
we would have humanized
you would have humanized
they would have humanized
ThesaurusAntonymsRelated WordsSynonymsLegend:
Verb1.humanize - make more humane; "The mayor tried to humanize life in the big city"
alter, change, modify - cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue"
dehumanise, dehumanize - deprive of human qualities; "Life in poverty has dehumanized them"

humanize

verb civilize, improve, refine, polish, educate, soften, cultivate, tame, reclaim, enlighten, mellow He used what discretion he could to modify or humanize the system.

humanize

verb
To fit for companionship with others, especially in attitude or manners:
Translations

humanize

[ˈhjuːmənaɪz] VThumanizar

humanize

[ˈhjuːmənaɪz] humanise (British) vt [+ situation, condition] → humaniser

humanize

References in periodicals archive ?
Antitope will produce a range of fully humanized antibodies using its Composite Human Antibody technology that are designed to bind to and inhibit the function of LRG1.
NovelMed will provide an overview of its platform of high-affinity, humanized antibodies for the treatment of inflammatory, ophthalmic, and hemolytic diseases.
The company says Asterand scientists have developed a highly sensitive IHC technique for testing human or humanized antibodies being considered as drug candidates for possible side effects.
Protein Design Labs is a leader in the development of therapeutic humanized antibodies for the prevention or treatment of cancer and certain immunologic disorders.
With further genetic engineering, immunologists have of late created more humanized antibodies in mice, but the animals still can't synthesize adequate amounts.
We are very pleased with this outcome as it demonstrates the efficiency with which Aragen Bioscience's clients can access the value of XOMA's Human Engineering([TM]) platform and its ability to provide high quality humanized antibodies for development purposes," commented Aragen President and Chief Executive Officer Rick Srigley.
They have developed a number of advanced proprietary technologies that allow them to create humanized antibodies that can be used either alone in unlabeled or "naked" form, or conjugated with radioactive isotopes, chemotherapeutics, cytokines or toxins, in each case to create highly targeted agents.
Apexigen will assume development and commercialization of therapeutic "bio-better" product programs initiated by Epitomics, including humanized antibodies against VEGF and TNF.
Fremont, CA; 510-574-1419) announced that it has granted a non-exclusive license under its antibody humanization patents to Celltech for humanized antibodies against tumor necrosis factor-alpha, believed to be an important factor in the inflammatory process in humans.
The contract with Cytovance represents a major step forward for Selexys as we move our portfolio of engineered humanized antibodies towards clinical development," said Richard Alvarez, chief operating officer of Selexys.
The joint venture will have the exclusive rights to the intellectual property, which includes patents on a proprietary technology using atomic structure for antibody humanization to rapidly and cost-effectively create humanized antibodies which retain high affinity and avoid immunogenicity.