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Huntington's disease

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
Hun·ting·ton's disease  (hntng-tnz)
n.
A rare inherited disease of the central nervous system characterized by progressive dementia, abnormal posture, and involuntary movements. The typical age of onset is between 30 and 50 years. Also called Huntington's chorea.

[After George Huntington (1851?-1916), American physician.]

Huntington's disease [ˈhʌntɪŋtən]
n
(Medicine / Pathology) a rare hereditary type of chorea, marked by involuntary jerky movements, impaired speech, and increasing dementia Former name Huntington's chorea
[named after George Huntington (1850-1916), US neurologist]
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.Huntington's disease - hereditary disease; develops in adulthood and ends in dementia
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
chorea - any of several degenerative nervous disorders characterized by spasmodic movements of the body and limbs
autosomal dominant disease, autosomal dominant disorder - a disease caused by a dominant mutant gene on an autosome


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Huntington's disease is a neurodegenerative disorder with a genetic basis.
Scientists identified a mutant form of the protein huntingtin as the culprit in Huntington's disease in 1993.
The cell lines have been produced over a period of several years under varying conditions, and conversion to a standard methodology is expected to facilitate their use in Huntington's disease-related research towards the development of new Huntington's disease drugs and diagnostics.
 
 
 
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