Patients presenting with corneal ectasia (for example keratoconus, pellucid marginal degeneration), corneal dystrophies (for example epithelial basement membrane dystrophy, Fuchs' endothelial dystrophy), recurrent corneal erosions, corneal hypoaesthesia
, active corneal inflammation or active corneal infection are regarded as unsuitable candidates.
Adverse Effects: Very common effects in ABRAXANE monotherapy: Neutropenia, anaemia, leukopenia, thrombocytopenia, lymphopenia, bone marrow suppression, peripheral neuropathy, neuropathy, hypoaesthesia
, paraesthesia, myalgia, arthralgia, asthenia, nausea, vomiting, diarrhoea, constipation, stomatitis, anorexia, pyrexia, alopecia, rash, fatigue, mucositis.
Most common side effects ([greater than or equal to]1/10) caused by ABRAXANE include; neutropenia, anemia, leucopenia, thrombocytopenia, lymphophenia, anorexia, peripheral neuropathy, hypoaesthesia
, paraethesia, nausea, diarrhoea, vomiting, constipation, stomatitis, alopecia, rash, arthralgia, myalgia, fatigue, asthenia, pyrexia.
occurs with sensory hypersensitivity in chronic whiplash--Further evidence of a neuropathic condition.