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A cytokine released by T cells that promotes the proliferation of a wide variety of blood cell types.
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The new service, hosted on FCO Services' Government Secure Application Environment (GSAE) cloud infrastructure, is expected to enable UK government organisations to collaborate securely on classified content up to and including IL3 (also known as 'RESTRICTED').
Drugs (or isolated biologicals in clinical use or trials): IL1, IL3, IL6, Stem Cell Factor(s), erythropoietin, G-CSF, etc.
Oct-1 plays a major role in controlling housekeeping genes and tissue-specific genes, including genes encoding several other cytokines: TNF-[tumor necrosis factor (TNF superfamily, member 2)] (32), IL2 (interleukin 2) (33), IL3 [interleukin 3 (colony-stimulating factor, multiple)], IL5 [interleukin 5 (colony-stimulating factor, eosinophil)], CSF2 [colony stimulating factor 2 (granulocyte-macrophage)] (34), and IL8 (interleukin 8) (35).
Como antiinflamatorios, los glucocorticoides logran la reduccion de la concentracion, distribucion y funcion de los leucocitos perifericos, de la sintesis de prostaglandinas, leucotrienos, enzimas proinflamatorias, produccion de peroxido por los neutrofilos, eosinofilos e inmunoglobulinas, desencadenando la apoptosis y disminuyendo factores quimiotacticos, como la IL3, IL5 (7).
Both pre-formed and newly synthesized lipid mediators, as well as other cytokines like IL3, 5, and granulocyte macrophage-colony stimulating factor, will attract other inflammatory white cells--basophils and eosinophils, but not neutrophils--to the local site of the reaction, causing further and prolonged damage to the tissue.
Se sugiere que la migracion de eosinofilos en la piel pueda ser mediada por una quemoquina inducida por Th2, la eotaxina, la cual actuaria sinergicamente con TNFa y con IL3, IL4 e IL5 provenientes del infiltrado dermico de celulas T en las lesiones tempranas de DH.
IL3 can potentially be used in the treatment of a plastic and other anaemia.
TABLE 6 Proportional Change in Percentage of Establishments Below a CertainSize and Total Employment Growth in 59 Canadian Metropolitan Areas Stage 1G=IL, GLM model (5)Class Geo effect IL1 IL2 IL3 IL4 IL5 IL6 IL7Sign (+/-) - - - - + + +Significance (1) (2) (2) (2) (4) (3) (4) --R (5) 0.