heavy chain

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heavy chain

n.
Either of the two larger polypeptide chains in an immunoglobulin molecule, consisting of a variable region that contains the antigen-binding portion and a constant region that is specific to each immunoglobulin class or subclass.

heavy chain

n
(Medicine) immunol a type of polypeptide chain present in an immunoglobulin molecule
References in periodicals archive ?
Somatic mutation in the rearranged variable regions of immunoglobulin heavy chains (IgVH) has been reported to be of prognostic importance since 1999.
Five types of immunoglobulin heavy chains have been identified: gamma, alpha, mu, delta and epsilon.
The antisera specificities in this assay were reported to be 10 000-fold higher for FLCs than for light chains bound to immunoglobulin heavy chains.

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