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penetrance |
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penetrance [ˈpɛnɪtrəns] n (Life Sciences & Allied Applications / Genetics) Genetics the percentage frequency with which a gene exhibits its effect [from penetr(ant) + -ance, on the model of German penetranz] How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| In recent years, however, geneticists have begun to suspect that Hirschsprung's disease follows a pattern called autosomal dominance with incomplete penetrance. The condition affects 1:2,000 to 1:10,000 newborns and is passed to offspring as a mendelian recessive with incomplete penetrance. Paigen, the Jackson Laboratory scientist who directs Nishina and Naggert's research, says a genetic phenomenon called incomplete penetrance could account for the fact that myocardial infarctions strike mostly men and postmenopausal women. |
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