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Related to Inhibin B: Inhibin A, Anti mullerian hormone


A peptide hormone secreted by the follicular cells of the ovary and the Sertoli cells of the testis that inhibits secretion of follicle-stimulating hormone from the anterior pituitary.


(Biology) biology a peptide hormone, produced by both the ovary and the testis, that inhibits (and thus regulates) the production of FSH (follicle-stimulating hormone)


(ɪnˈhɪb ɪn)
a male hormone that acts on the pituitary gland to limit the secretion of FSH.
[1980–85; inhib (it) + -in1]
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Net increase in stimulatory input resulting from a decrease in inhibin B and an increase in activin A may contribute in part to the rise in follicular phase follicle-stimulating hormone of aging cycling women.
Longitudinal reproductive hormone profiles in infants: peak of inhibin B levels in infant boys exceeds levels in adult men.
The authors report that men exposed to dioxin throughout the perinatal period had reduced semen quality and sperm counts, increased concentrations of follicle-stimulating hormone, and decreased inhibin B concentrations.
Inhibin B could be used as a marker for the identification of spermatogenesis and as an indicator for the level of interruption in spermatogenesis in men with non-obstructive azoospermia (12).
Fluctuations of E2, decreased levels of inhibin b, and increased FSH levels were associated with these symptoms.
In 2000, MFS became the first clinic in Britain to use Inhibin B to assess a woman's ovarian reserve, which can help gauge a woman's fertility age - or how long they can safely defer motherhood.
But a study presented in a poster session at the annual meeting of the Endocrine Society indicates that increasing body mass index (BMI) in males is associated with decreased testosterone and inhibin B levels.
BMI and skinfold thickness were negatively correlated with serum testosterone level, while inhibin B and FSH were negatively correlated with BMI.
It has been difficult to design assays that distinguish Inhibin A from other, structurally similar transforming growth factor-[beta] superfamily proteins, particularly the free a subunits, Inhibin B and activin A.
Associations with lead were estimated for luteinizing hormone in 671 girls and inhibin B in 655 girls.
Previous studies (7, 20, 21) showed that inhibin A was detected in 20% of mucinous tumors and 77% of granulosa cell tumors, whereas inhibin B was detected in 60% of mucinous tumors (21) and 100% of granulosa cell tumors.