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COX-2 inhibitor
(redirected from Inhibition of COX-2)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
COX-2 inhibitor  (kkst)
n.
Any of a class of nonsteroidal anti-inflammatory drugs that selectively block prostaglandin formation so as to cause minimal gastrointestinal side effects.

[From c(yclo)ox(ygenase)-2, enzyme involved in the production of prostaglandins.]
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.Cox-2 inhibitor - an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks; "Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys"
anti-inflammatory, anti-inflammatory drug - a medicine intended to reduce inflammation
Celebrex, celecoxib - a Cox-2 inhibitor (trade name Celebrex) that relieves pain and inflammation without harming the digestive tract
rofecoxib, Vioxx - a Cox-2 inhibitor (trade name Vioxx) that relieves pain and inflammation without harming the digestive tract; voluntarily withdrawn from the market in 2004
Bextra, valdecoxib - a Cox-2 inhibitor (trade name Bextra) that relieves pain and inflammation without harming the digestive tract


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Ibuprofen has demonstrated anticancer effects, most probably due to its inhibition of COX-2, another enzyme that cancer cells use to facilitate their growth and survival.
The results of the present study, therefore, would suggest that the inhibition of COX-2 maybe play a key role in the inhibition of [PGF.
evidence that inhibition of COX-2 can reduce damage to normal tissues in conventional lung cancer therapy; treatment of mantle cell lymphoma ands central nervous system lymphoma; nerve-sparing radical hysterectomy to preserve bladder function in invasive cervical cancer; and the use of nanoparticles in treating tumors.
 
 
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Inhibition of cyclo-oxygenase 2
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Inhibition of cyclooxygenase-2 activity
Inhibition of cyclooxygenase-2 activity
Inhibition of Incoming Forwarded Calls
Inhibition of Passive Hemagglutination
inhibition of reflexes
 
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