The innate immune system
is fundamentally important to human health.
Lirilumab, which is licensed to Bristol-Myers Squibb, is targeted against the inhibitory killer-cell immunoglobulin-like receptors (KIRs) that are expressed predominantly on natural killer (NK) cells, which belong to the innate immune system
The company is developing synthetic ligands of a novel receptor of the innate immune system
, Retinoic acid Inducible Gene I (RIG-I), which recognizes viral RNA.
The researcher said that toll-like receptor 4, a biological messenger, helps control activation of the innate immune system
His topics include the innate immune system
, cytokines, immunology of the airways, immunology of the skin, immunity to fungi, disorders of the immune system, and vaccinations.
A new study published today as the cover story in the journal Nature features Biothera's beta glucans and new discoveries about how these unique immunodulating compounds prime the innate immune system
to protect the body.
Tefinostat is a highly potent, innovative oral histone deactylase (HDAC) that selectively targets macrophages and monocytes - central cells of the innate immune system
While the effects of proteins and peptides on the adaptive immunity have been examined in a number of studies, few have studied how these molecules are absorbed through the small intestine and interact with the innate immune system
NLRP12 belongs to a family of proteins best known for working in the innate immune system
to help cells sense threats and then launch the inflammatory response to eliminate them.
The report describes that a protein called GEF-H1 is essential to the ability of macrophages - major contributors to the innate immune system
- to respond to viral infections like influenza.
Innate immune system
of skin and oral mucosa; properties and impact in pharmaceutics, cosmetics, and personal care products.
Based in Eagan, Minnesota, the company is developing pharmaceuticals that engage the innate immune system
to fight cancer.