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inosine
(redirected from Inosine monophosphate)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
in·o·sine  (n-sn, -sn, n-)
n.
A nucleoside formed by the deamination of adenosine or the hydrolysis of inosinic acid.

[Greek s, n-, sinew; see wei- in Indo-European roots + -os(e) + -ine.]
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.inosine - a nucleoside that is formed by the deamination of adenosine; used in kidney transplantation to provide a temporary source of sugar
nucleoside - a glycoside formed by partial hydrolysis of a nucleic acid


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The structure, activity, and mechanisms of inosine monophosphate dehydrogenase, a central enzyme of purine biosynthesis, are explained.
Inosine is synthesized as inosine monophosphate by means of a complex series of biochemical reactions.
9,10) Mycophenolate mofetil is the 2-morpholinoethyl ester of mycophenolic acid (MPA), a potent and selective noncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPD), a key enzyme in the de novo synthesis of guanosine nucleotides.
 
 
 
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