interleukin

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Related to Interleukin-17: IL-17F

in·ter·leu·kin

 (ĭn′tər-lo͞o′kĭn)
n.
Any of various small proteins that are produced by a variety of cell types, especially T cells and other white blood cells, and that regulate many aspects of inflammation and the immune response, including stimulating the production of white blood cells and platelets.

interleukin

(ˌɪntəˈluːkɪn)
n
(Biochemistry) a substance extracted from white blood cells that stimulates their activity against infection and may be used to combat some forms of cancer

in•ter•leu•kin

(ˈɪn tərˌlu kɪn)
n.
any of a family of small proteins that participate in the body's defense system, esp. by promoting the growth and activation of white blood cells.
[1979; inter- + leuk (ocyte) + -in1; so called because such proteins act as agents of communication between different populations of leukocytes]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
References in periodicals archive ?
About brodalumab Brodalumab is a novel human monoclonal antibody that binds to the interleukin-17 (IL-17) receptor and inhibits inflammatory signaling by blocking the binding of several IL-17 ligands to the receptor.
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis.
Interleukin-15 induces interleukin-17 production by synovial T cell lines from patients with rheumatoid arthritis.
Brodalumab is the only investigational treatment in development that binds to the interleukin-17 (IL-17) receptor and inhibits inflammatory signaling by blocking the binding of several IL-17 ligands to the receptor.
Investigators hypothesized that SIBO might modulate cytokines by increasing tumor necrosis factor-alpha, suppressing interleukin-17, or increasing the T helper cell type 1 pathway gene to drive skin inflammation.
Interleukin-17 levels in the sera and synovial fluid from the rheumatoid arthritis patients and control subjects Groups Cases IL-17 levels (pg/ml) Healthy control sera 20 17.
com)-- Dermatology Therapeutics Market to 2018 - Novel Biologics Targeting Interleukin-17 Receptor Presents New Options in Psoriasis Treatment
A particularly interesting observation was that although CD20 mAb treatment decreased interferon-y production in spleen T cells, it also enhanced interleukin-17 (IL-17) production.
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17.
Role of interleukin-17 and interleukin-17-induced cytokines interleukin-6 and interleukin-8 in unstable coronary artery disease.
Ensemble's internal discovery and development efforts are focused on the key therapeutic areas of oncology and immuno-inflammatory diseases, with its lead program, a small molecule antagonist of Interleukin-17, a cytokine implicated in multiple inflammatory and autoimmune diseases, poised to enter development with an orally active candidate in 2013.