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interleukin
(redirected from Interleukins)

   Also found in: Medical, Encyclopedia, Wikipedia, Hutchinson 0.03 sec.
interleukin [ˌɪntəˈluːkɪn]
n
(Life Sciences & Allied Applications / Biochemistry) a substance extracted from white blood cells that stimulates their activity against infection and may be used to combat some forms of cancer

interleukin  (ntr-lkn)
Any of a class of cytokines that act to stimulate, regulate, or modulate lymphocytes such as T cells. Interleukin-1, which has two subtypes, is released by macrophages and certain other cells, and regulates cell-mediated and humoral immunity. It induces the production of interleukin-2 by helper T cells and also acts as a pyrogen. Interleukin-2 stimulates the proliferation of helper T cells, stimulates B cell growth and differentiation, and has been used experimentally to treat cancer. Interleukin-3 is released by mast cells and helper T cells in response to an antigen and stimulates the growth of blood stem cells and lymphoid cells such as macrophages and mast cells. There are many other interleukins that are part of the immune system.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)


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? Mentioned in ? References in periodicals archive
 
TECKI CCL25), and interleukins such as IL-10 and IL-5, indicating a possible involvement of DU in cancer development, autoimmune diseases, and T helper 2 polarization ofT cells.
After T-cell receptor stimulation, most patients also experience a decrease in the production of interleukins, possibly because of a defect in the signal transduction system of CD4 T cells.
Cytokine: proteins (such as interleukins, tumor necrosis factor, and interferons) that are secreted by immune cells.
 
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