Isonicotinic

Related to Isonicotinic: Isonicotinic acid hydrazide

I`so`nic`o`tin´ic


a.1.(Chem.) Pertaining to, or derived from, isonicotine.
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Determination of Isonicotinic Acid Hydrazide [isoniazid] using N-bromosuccinimide.
INH, the hydrazide of isonicotinic acid, has been the mainstay of TB treatment and prevention since the 1950s.
Isonicotinic acid hydrazide (INH) is usually the suspected drug for this side effect.
Positive Oxyphenbutazone 16 07 Phenylbutazone 08 03 Acetyl salicylic acid 09 -- Analgin 13 01 Sulphadiazine 09 01 Sulphadimethoxine 07 -- Trimethoprim 11 -- Sulphamethoxazole 11 02 Dapsone 08 -- T etracycline 09 -- Oxytetracycline 06 -- Doxycycline 08 -- Paracetamol 02 -- Isonicotinic acid hydrazide 01 -- Thiacetazone 01 01 Procaine penicillin 08 --
4 Isoniazid is acetylated by the liver enzyme N- acetyltransferase 2 (NAT2) and then hydrolyzed resul- ting in formation of isonicotinic acid and acetylhydra- zine; the later compound is activated by cytochrome P-450.
The government will supply the drugs to designated chemists and will also give them incentives for distributing four drugs including Isonicotinic Hydrazide ( INH).
Braga et al [8] reported the use of mechanochemical method for the synthesis of Cu(INA)2 by grinding of copper acetate and isonicotinic acid.
The reagent diacetyl monoxime isonicotinoyl hydrazone (DMIH) was prepared by simple condensation of diacetyl monoxime and isonicotinic hydrazide in 1:1 mole ratio and its structure is given in Figure 1.
The 3HP group was given once-weekly, directly observed treatment with rifapentine (brand name Priftin; 900 mg) plus isoniazid (brand name Nydrazid, also known as isonicotinic acid hydrazide or INH; 15-25 mg/kg) for 3 months.
The 3HP group was given once weekly, directly observed treatment with rifapentine (brand name Priftin; 900 mg) plus isoniazid (brand name Nydrazid, also known as isonicotinic acid hydrazide or INH; 15-25 mg/kg) for 3 months.
Good examples of vitamin antagonists include isonicotinic acid hydrazide (antagonist of pyridoxine), aminopterin (folate antagonist), dicumarol (vitamin K antagonist), and avidin (interferes with biotin absorption).