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keratin
(redirected from Keratins)

   Also found in: Medical, Encyclopedia, Wikipedia, Hutchinson 0.03 sec.
ker·a·tin  (kr-tn)
n.
A tough, insoluble protein substance that is the chief structural constituent of hair, nails, horns, and hooves.

[Greek keras, kert-, horn; see ker-1 in Indo-European roots + -in.]

ke·rati·nous (k-rtn-s) adj.

keratin
Noun
a fibrous protein found in the hair and nails

keratin  (kr-tn)
Any of a class of tough, fibrous proteins that are the main structural component of hair, nails, horns, feathers, and hooves. Keratins are rich in sulfur-containing amino acids, especially cysteine. Individual keratin molecules are entwined helically around each other in long filaments, which are cross-linked by bonds between sulfur atoms on different chains. The twining and cross-linking produce strength and toughness.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.keratin - a fibrous scleroprotein that occurs in the outer layer of the skin and in horny tissues such as hair, feathers, nails, and hooves
feather, plumage, plume - the light horny waterproof structure forming the external covering of birds
hair - a covering for the body (or parts of it) consisting of a dense growth of threadlike structures (as on the human head); helps to prevent heat loss; "he combed his hair"; "each hair consists of layers of dead keratinized cells"
horn - the material (mostly keratin) that covers the horns of ungulates and forms hooves and claws and nails
albuminoid, scleroprotein - a simple protein found in horny and cartilaginous tissues and in the lens of the eye


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? Mentioned in ? References in periodicals archive
 
Cell lines derived from the tumors formed by injection of arsenite-exposed HaCaT cells into nude mice expressed higher levels of keratin 6, a proliferation marker of keratinocytes, than did parental HaCaT cells, whereas the expression of keratins 5, 8, and 10 was significantly decreased.
The tumor cells were also positive for keratins (AE1/AE3 and 35BH11), but they were negative for melanoma-specific antigen (HMB45) and CD34 (QBEND/10).
Keratinocytes produce keratins, proteins that help give skin its protective properties, says Dr.
 
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