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keratin |
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keratin Noun a fibrous protein found in the hair and nails
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| Cell lines derived from the tumors formed by injection of arsenite-exposed HaCaT cells into nude mice expressed higher levels of keratin 6, a proliferation marker of keratinocytes, than did parental HaCaT cells, whereas the expression of keratins 5, 8, and 10 was significantly decreased. The tumor cells were also positive for keratins (AE1/AE3 and 35BH11), but they were negative for melanoma-specific antigen (HMB45) and CD34 (QBEND/10). Keratinocytes produce keratins, proteins that help give skin its protective properties, says Dr. |
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