We further investigated possible alterations of Kiss1
gene expression levels upon DEHP exposure by quantifying the number of GFP-positive cells in mice exposed to vehicle or DEHP from a line expressing GFP under the control of the Kiss1
Furthermore, mRNA expression of Leptin, LEPR, JAK2, STAT3, KISS1
and TRPC5 were detected in the adipose and hypothalamic tissue of pre-puberty and puberty onset goats, respectively, by Real-time PCR, which was aimed to see whether the changes of adipose affect the ability of leptin to activate signaling pathways and modulate the expression of hypothalamic genes involved in reproduction and metabolism.
Hypogonadotropic hypogonadism due to loss of function of the KiSS1
-derived peptide receptor GPR54.
Likewise, the recently identified involvement of epigenetics in the control of Kiss1
expression at puberty, a crucial stage in sexual development that is metabolically gated, suggests also the contribution of these regulatory mechanisms to this phenomenon.
Kisspeptin is derived from a 145-amino acid precursor which is encoded by Kiss1
gene and is mainly expressed in hypothalamus and placenta .
The gene expression of KISS1
gene in the hypothalamus of Bama miniature pigs reduced significantly (p<0.
Developmental changes in hypothalamic Kiss1
expression during activation of the pulsatile release of luteinising hormone in maturing ewe lambs.
Updated, this edition has homeostasis highlights beginning each chapter; more art, new figures, and more electron micrographs; new questions at the ends of sections; new content on the discovery of tunneling nanotubes, the default mode network, global workspace theory, the synaptic homeostasis hypothesis, and the influence of kisspeptin signals from kiss1
neurons in the control of gonadotropin releasing hormone secretion; more on innate immunity and brown fat; and online tutorials and animations and virtual physiology labs.
Depending on age and sex, five genes in the hypothalamus were affected by PCB treatment: Kiss1
(which stands for kisspeptin 1), Kiss1r (kisspeptin 1 receptor), Gper (G-protein-coupled estrogen receptor), Tac2 (neurokinin B) and Pdyn (prodynorphin).
Kisspeptin, a peptide that activates the kisspeptin receptor, is encoded by the KISS1
(KiSS-1 metastasis-suppressor) gene.
Sex steroid control of hypothalamic Kiss1
expression in sheep and rodents: comparative aspects.
Ambos han sido implicados tanto en el desarrollo de cancer de seno como en asociaciones con cambios numericos especificos para esta neoplasia, tales como ARHC, P73, MUC1 y KISS1
en el cromosoma 1 y en el cromosoma 17 el oncogen ERBb2 (13) (14) (15), los genes supresores de tumor BCPR y NME1 y los genes reparadores de danos al ADN: p53 y BRCA1.