L-dopa


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Related to L-dopa: levodopa, dopamine, Mucuna pruriens

L-do·pa

 (ĕl-dō′pə)
n.
An isomer of dopa that is converted in the brain to dopamine and is used in synthetic form to treat Parkinson's disease. Also called levodopa.

L-dopa

(ɛlˈdəʊpə)
n
(Biochemistry) a substance occurring naturally in the body and used to treat Parkinson's disease. Formula: C9H11NO4. Also called: levodopa
[C20: from L-d(ihydr)o(xy)p(henyl)a(lanine)]

L-do•pa

(ˌɛlˈdoʊ pə)

n.
the levorotatory isomer of dopa, converted in the brain to dopamine: used in synthetic form chiefly for treating parkinsonism. Also called levodopa.
[1935–40]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.L-dopa - the levorotatory form of dopa (trade names Bendopa and Brocadopa and Larodopa); as a drug it is used to treat Parkinson's disease
dihydroxyphenylalanine, dopa - amino acid that is formed in the liver and converted into dopamine in the brain
References in periodicals archive ?
It was designed to deliver a precise dose of a dry powder formulation of L-dopa to the lung.
It is commonly used in conjunction with L-dopa to help control serious motor complications and dyskinesias that frequently occur in patients after several years of L-dopa treatment.
As most patients in these studies were treated with a combination of L-DOPA and carbidopa, it is possible that one or both of these drugs could exhibit anti-cancer properties and contribute to the lower incidence of cancer observed in these patients.
However, it is hard to distinguish that the circadian disturbance in patients is due to the disease progression itself, or is affected by L-DOPA replacement therapy.
While findings can lead to new treatments to decrease alpha-synuclein levels, researchers say continuing treatment with L-Dopa, which replenishes doparnine in the brain, remains standard care.
The granted claims covering multiple dosage forms of AV-101, treatment of depression and reduction of dyskinesias associated with L-DOPA treatment of Parkinson's disease will be in effect until at least January 2034.
Existen formas autosomicas recesivas, clinicamente mas severas, con compromiso cognitivo y retraso del desarrollo psicomotor, producidas por mutaciones de la misma GTP--I, de la tirosina hidroxilasa y de la sepiapterina reductasa y que no responden bien a la L-dopa.
The synthesis of catecholamine is a complex process and involves conversion of tyrosine to L-Dopa by the enzyme TH.
L-dopa production was found optimal when L-ascorbic acid (5 mg/ml) was added 6 min after starting the reaction (120 rpm).
The book relates how his diagnosis--toxin-tainted opium--and the race to find a longer-term solution than L-dopa could provide led to the recovery of two of his patients after they received fetal-tissue transplants.