LDL


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LDL

(ĕl′dē′ĕl′)
n.
A lipoprotein with a relatively high proportion of lipids and low proportion of protein that incorporates cholesterol and transports it to cells. High levels are associated with an increased risk of atherosclerosis and coronary artery disease. Also called LDL cholesterol.

[l(ow-)d(ensity) l(ipoprotein).]

LDL

abbreviation for
(Biochemistry) low-density lipoprotein

LDL

low-density lipoprotein: a plasma protein that is the major carrier of cholesterol in the blood, with high levels being associated with atherosclerosis.
[1975–80]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.LDL - a lipoprotein that transports cholesterol in the blood; composed of moderate amount of protein and a large amount of cholesterol; high levels are thought to be associated with increased risk of coronary heart disease and atherosclerosis
lipoprotein - a conjugated protein having a lipid component; the principal means for transporting lipids in the blood
LDL cholesterol - the cholesterol in low-density lipoproteins; the `bad' cholesterol; a high level in the blood is thought to be related to various pathogenic conditions
Translations

LDL

abbr low density lipoprotein. V. lipoprotein.
References in periodicals archive ?
Along with other factors, a high LDL level contributes to atherosclerosis, the formation of artery-clogging plaques responsible for heart attack and ischemic stroke.
The Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) trial was the pivotal efficacy and safety study for the proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitor evolocumab (Repatha) and enrolled patients with atherosclerotic cardiovascular disease and LDL cholesterol levels of at least 70 mg/dL (N Engl J Med.
The team notes that trials specifically investigating how PCSK9 inhibitors affect cardiovascular outcomes have yet to be completed, so data for these drugs to date were assessed separately and compared with data for therapies that increase LDL receptor expression.
3) Atherosclerosis is initiated by the accumulation of oxidatively modified LDL within plaques, which release ROS.
Antibodies against human lipoproteins were used to form antigen - antibody complexes with LDL (low density lipoproteins), VLDL (very low density lipoproteins) and Chylomicrons in a way that only HDL-cholesterol is selectively determined by an enzymatic cholesterol measurement.
Data demonstrating a more reliable measure of LDL quantity--LDL particle number (LDL-P)--that can identify statin-treated individuals with continued LDL-related ASCVD risk and guide therapy adjustment likely to result in additional reduction in ASCVD events
Following BRB damage, extravasation of LDL in the extracellular tissue modifies LDL further through oxidation and glycation, making it more toxic towards retinal cells.
The best way to lower your LDL is to make sure your diet includes lean protein and healthy fats, found in fish, olive oil, and nuts and seeds.
HDL is thought to protect heart health--but LDL harms it.
The Friedewald formula underestimates LDL cholesterol at low concentrations.
Researchers also observed that the avocado diet significantly lowered small, dense LDL cholesterol (a more atherogenic subclass of LDL) and oxidized LDL (atherogenic modified LDL particle).
Emerging at the forefront of LDL-related (low density lipoprotein) cardiovascular disease management is nuclear magnetic resonance (NMR), a technology that is quickly being adopted by physicians across the country and changing the standard of care in LDL management.