light chain

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light chain

n.
Either of the two smaller polypeptide chains in an immunoglobulin molecule, consisting of an antigen-binding portion with a variable amino acid sequence and a constant region that occurs in two different forms in humans.
References in periodicals archive ?
Monoclonal gammopathy of undetermined significance: Apropos of a case of lambda light chain deposition nephropathy
The company's new resin, LambdaFabSelect, is a designed tool for the GMP-regulated purification of antibodies and antibody fragments that contain a lambda light chain.
Trimolecular complexes of lambda light chain dimers in serum of a patient with multiple myeloma.
Sensitive probes include: Epstein-Barr encoded RNA (EBER), kappa light chain, lambda light chain, dual kappa/lambda, IgA-alpha heavy chain, IgG-gamma heavy chain, IgM-mu heavy chain, and ribosomal RNA (positive control).
These cells express IgM and show lambda light chain restriction.
In summary, the patient has a mild plasmacytosis on the biopsy (-5-10%) that is lambda light chain restricted.
Assessment of cerebrospinal fluid immunoglobulin patterns after isoelectric focusing: use of kappa and lambda light chain immunoperoxidase staining.
Detection of kappa and lambda light chain monoclonal proteins in human serum: automated immunoassay versus immunofixation electrophresis.