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leukotriene
(redirected from Leukotrienes)

    Also found in: Medical, Encyclopedia, Wikipedia, Hutchinson 0.03 sec.
leu·ko·tri·ene  (lk-trn)
n.
Any of several lipid compounds that contain 20 carbon atoms, are related to prostaglandins, and mediate the inflammatory response.
[leuko(cyte) + triene, a compound containing three double bonds (tri- + -ene).]
leukotriene [ˌluːkəʊˈtraɪiːn]
n
(Life Sciences & Allied Applications / Biochemistry) one of a class of products of metabolic conversion of arachidonic acid; the active constituents of slow-reacting substance, responsible for bronchial constriction, contraction of smooth muscle, and inflammatory processes
[from leukocyte, in which they were discovered + triene from the conjugated triene unit that they contain]


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Among the inflammatory mediators released from mast cells, cysteinyl leukotrienes (cysLTs) have been shown to cause airway inflammation and airway smooth muscle contraction during RSV infection, accounting for the wheezing observed in bronchiolitis.
How exposures to biologics influence the induction and incidence of ... by Peden, David / Environmental Health Perspectives
This results from the inability of phagocyte oxidase to degrade inflammatory mediators such as leukotrienes, complement, and perhaps other components.
Human granulocytic anaplasmosis and Anaplasma phagocytophilum by Bakken, Johan S. / Emerging Infectious Diseases
The antibodies signal mast cells and basophils to release inflammatory chemicals such as histamine, prostaglandins and leukotrienes, which, in turn, trigger allergy-related symptoms like runny nose, scratchy eyes and sneezing.
Indoor allergens & women's health by National Women's Health Report
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