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leukotriene
(redirected from Leukotrienes)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
leu·ko·tri·ene  (lk-trn)
n.
Any of several lipid compounds that contain 20 carbon atoms, are related to prostaglandins, and mediate the inflammatory response.

[leuko(cyte) + triene, a compound containing three double bonds (tri- + -ene).]

leukotriene [ˌluːkəʊˈtraɪiːn]
n
(Life Sciences & Allied Applications / Biochemistry) one of a class of products of metabolic conversion of arachidonic acid; the active constituents of slow-reacting substance, responsible for bronchial constriction, contraction of smooth muscle, and inflammatory processes
[from leukocyte, in which they were discovered + triene from the conjugated triene unit that they contain]


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The gene expression of enzymes COX-2, 5-LOX, FLAP and COX-1 were monitored and the products these enzymes generate, prostaglandins and leukotrienes, were quantified.
Leukotriene Modifiers Leukotrienes are derived from arachidonic acid and are preformed mediators located within mast cells.
Addition of the eicosatetraenoid products of 5-lipoxygenase (5-HETEs) showed stimulation of prostate cancer cell growth similar to that of arachidonic acid, whereas the leukotrienes were ineffective.
 
 
 
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