Changes in testosterone levels in diabetic men may be related to alterations in the Leydig
cell function (ARIKAWE et al.
The development of the internal genitalia is dependent on the production, or lack of, of hormones from the foetal testis; both testosterone from the Leydig
cells and anti-Mullerian hormone (AMH) from the embryonic Sertoli cells are needed.
After delivery, an increase in the number of Leydig
Reduced number of sperm count and excessive destruction of testicular follicles including destruction of spermatids leydig
cells and sertoli cells were also seen in both groups.
Furthermore, Cisplatin was established to cause functional disorders in Leydig
cells and induced infertility because of irreparable damage caused to the stem cells colony .
Researchers have shown that the cells responsible for producing testosterone in adults - known as Leydig
cells - are derived from a specific population of stem cells found in the testes.
It has been shown that reactive oxygen species (ROS) can inhibit the steroid hormone production of cultured leydig
cells by directly affecting the steroidogenic enzymes.
Group I, normal control rats (Figure 5(a)), shows normal spermatogonia, Sertoli cells, and Leydig
cells with accumulation of spermatozoa within the seminiferous tubules.
Muller, 1776) Bosmina (Eubosmina) coregoni Baird, 1857 Bosmina (Eubosmina) + + + crassicornis Lilljeborg, 1887 Bosmina (Eubosmina) + + longispina Leydig
, 1860 Bosmina (Eubosmina) reflexa + Seligo, 1907 Bythotrephes longimanus + + Leydig
, 1860 Polyphemus pediculus (Linnaeus, 1758) Leptodora kindtii (Focke, 1844) + + + Number of species 12 11 8 Species Dridzis Diaphanosoma brachyurum + (Lievin, 1848) Ceriodaphnia pulchella Sars, + 1862 Ceriodaphnia quadrangula (O.
The percentage of Leydig
cells was higher in summer compared to fall and winter.
Morphofunction features two compartments: (i) interstitial or intertubular, containing cells and fibers of connective tissue, blood and lymphatic vessels and Leydig
cells, the main source of androgen in the body, (ii) tubular, formed by seminiferous tubules, which are structured with its outer portion to the internal: tunica propria, the seminiferous epithelium and lumen (ROOIJ, 1998).
The result is lowered luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which lead to reduced testosterone production by Leydig
cells of the testis.