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ligase
(redirected from Ligases)

    Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
li·gase  (lgs, -gz)
n.
Any of a class of enzymes that catalyze the linkage of two molecules, generally utilizing ATP as the energy donor. Also called synthetase.
[Latin ligre, to bind; see leig- in Indo-European roots + -ase.]
ligase [ˈlaɪˌgeɪz]
n
(Life Sciences & Allied Applications / Biochemistry) any of a class of enzymes that catalyse the formation of covalent bonds and are important in the synthesis and repair of biological molecules, such as DNA


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? Mentioned in ? References in periodicals archive
 
The lack of measurable effects of PM on DNA strand breaks may be due to the very rapid repair by ligases, whereas guanine oxidation is repaired relatively slowly by base excision followed by strand nicking, insertion of nucleotide(s) in the gap, and rejoining by ligases (Hoeijmakers 2001; Risom et al.
Personal exposure to ultrafine particles and oxidative DNA damage by Loft, Steffen / Environmental Health Perspectives
These include restriction endonucleases for cleaving DNA and ligases for joining the fragments, recombinases that can execute a large variety of DNA cleavage and joining reactions.
Origin of genetic information and evolution of biological species by Wahid, Pallacken Abdul / Islam & Science
D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB.
Antimicrobial resistance gene delivery in animal feeds by Davies, Julian / Emerging Infectious Diseases
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