's major active metabolite, EXP-3174, is 10 to 20 times more potent than losartan
and has a longer duration of action (1).
The findings of this study indicate that losartan
therapy is noninferior to nifedipine at reducing Doppler echocardiographically measured PAP and improving exercise capacity in patients with secondary PHT.
Three additional studies examined the antihypertensive effects of losartan
and hydrochlorothiazide in combination.
Tenders are invited for Tablet Containing Losartan
50Mg Plus Hydrochlorothiazide 12.
They showed that losartan
, a drug normally prescribed for hypertension, could reverse the effects of early-stage liver failure in some patients.
CHICAGO -- Telmisartan provides greater reduction in proteinuria than losartan
does after 1 year of treatment in patients with hypertension and diabetic nephropathy, Dr.
Patients were randomized to receive treatment with either Micardis (telmisartan) 80mg or losartan
The results showed that plasma and urinary CTGF levels were elevated in non-diabetic proteinuric CKD patients, and urinary CTGF levels were reduced by sodium restriction, losartan
, and addition of the diuretic, hydrochlorothiazide, to losartan
In the study conducted using a rat model, the researchers assumed that that a compound similar to the anti-hypertensive drug losartan
can prevent the cognition loss that has been closely-associated with radiation therapy for brain tumour treatment.
CHICAGO -- The angiotensin II blocker losartan
, alone or in combination with the diuretic hydrochlorothiazide, appears efficacious in the treatment of obesity-associated hypertension, new data suggest.
Blood Pressure Goal Attainment: Comparative Efficacy of Olmesartan Medoxomil, Losartan
Potassium, Valsartan, and Irbesartan.
Duncia, currently with Bristol-Myers Squibb Pharma Company, was the lead chemist on the team that discovered losartan
(Cozaar(R)), an important new class of hypertensive drugs.