meth·o·trex·ate (m th  -trk s t)n. A toxic antimetabolite, C20H22N8O5, that acts as a folic acid antagonist to interfere with cellular reproduction and is used in the treatment of psoriasis, certain cancers, and certain inflammatory diseases such as rheumatoid arthritis. [methotre- (probably shortening and alteration of methylaminopterin, one of its chemical names : methyl + aminopterin) + perhaps (o)x(y)- + -ate.] |
methotrexate [ˌmɛθəʊˈtrɛkseɪt ˌmiːθəʊ-]
n
(Medicine / Pharmacology) an antimetabolite drug used in the treatment of certain cancers. Formula: C20H22N8O5
| methotrexate (mth-trkst) A toxic drug that acts as a folic acid antagonist to interfere with cellular reproduction and is used in the treatment of psoriasis, certain cancers, and certain inflammatory diseases, such as rheumatoid arthritis. Chemical formula: C20H22N8O5. |
ThesaurusLegend: Synonyms Related Words Antonyms
| Noun | 1. | methotrexate - toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis antimetabolite - an antineoplastic drug that inhibits the utilization of a metabolite immune suppressant drug, immunosuppressant, immunosuppressive, immunosuppressive drug, immunosuppressor - a drug that lowers the body's normal immune response |
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