mast cell

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mast cell

n.
A cell produced in bone marrow that functions in allergic reactions and other inflammatory and immune responses by releasing substances such as histamine and cytokines and by directly killing pathogens. Mast cells are found chiefly in connective tissue and contain basophilic granules.

[Partial translation of German Mastzelle, well-fed cell (from an early view that the granules were from phagocytosis) : Mast, food, mast (from Middle High German, from Old High German) + Zelle, cell.]

mast cell

n
(Biology) a type of granular basophil cell in connective tissue that releases heparin, histamine, and serotonin during inflammation and allergic reactions
[C19: from mast2, on the model of German Mastzelle]

mast′ cell`


n.
a large granular cell, common in connective tissue, that produces heparin, histamine, and serotonin.
[1885–90; partial translation of German Mastzelle=Mast mast2 + Zelle cell]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mast cell - a large connective tissue cell that contains histamine and heparin and serotonin which are released in allergic reactions or in response to injury or inflammation
connective tissue - tissue of mesodermal origin consisting of e.g. collagen fibroblasts and fatty cells; supports organs and fills spaces between them and forms tendons and ligaments
somatic cell, vegetative cell - any of the cells of a plant or animal except the reproductive cells; a cell that does not participate in the production of gametes; "somatic cells are produced from preexisting cells";
References in periodicals archive ?
Therefore, diagnosis must be confirmed by histopathologic studies, which allow visualizing the capsule of the fibrous connective tissue surrounding the granulomatous tissue and important cells such as lymphocytes, associated to plasma cells, neutrophils, histiocytes, an eventually mastocytes and eosinophils.
Review of the literature has suggested that serum tryptase may be considered as a new marker of the instability of atheromatous plaque with regard to the existence of mastocytes in heart tissue.
Abnormal overexpression of mastocytes in skin biopsies of fibromyalgia patients.