Meprin


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Noun1.Meprin - a sedative and tranquilizer (trade name Miltown and Equanil and Meprin) used to treat muscle tension and anxiety
antianxiety drug, anxiolytic, anxiolytic drug, minor tranquilizer, minor tranquilliser, minor tranquillizer - a tranquilizer used to relieve anxiety and reduce tension and irritability
brand, brand name, marque, trade name - a name given to a product or service
References in periodicals archive ?
Another protease, peptidyl arginine aldehyde protease, can also degrade BNP, and meprin was shown to lyse BNP in animal models but not in humans (26).
The enzyme, coded for by the MEP1A gene, is a zinc-containing metalloprotease called meprin, and is abundant in the intestine.
Successive action of meprin A and neprilysin catabolizes B-type natriuretic peptide.
The bioactive BNP 1-32 is further processed by receptors or enzymes like neprilysin, dipeptidyl peptidase IV, insulin degrading enzyme, meprin, and potentially other enzymatic pathways which may be identified in the future (4-6).
There are data showing that, in mice, meprin A, a protease expressed in kidney, may increase the effect of neprilysin by cleaving the first 6 N-terminal residues of mouse BNP (29).