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 (mĭ-tăl′ə-prōt′n-ās′, -āz′, -prō′tē-nās′, -nāz′)
Any of a group of proteolytic enzymes whose catalytic activity depends on the presence of a metal ion in the active site, especially any of those (called "matrix metalloproteinases") that degrade proteins in the extracellular matrix.
References in periodicals archive ?
Matrix Metalloproteinases in Health and Disease: Sculpting the Human Body
Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases.
Matrix metalloproteinases play critical roles in brain function and disease that have only recently received intensive study, said Dr.
Extracellular matrix metalloproteinases - MMPs, also referred to as matrixines, provide a group of proteolytic enzymes.
The elevation of cortisol inhibits fibroblast function and increases matrix metalloproteinases (collagenase, gelatinase).
Reduced matrix metalloproteinases (MMPs) activity is accompanied with extracellular matrix (ECM) accumulation in large arteries, leading to the hypertensive arterial remodeling in resistance arteries.
Matrix metalloproteinase7 (MMP-7) one of the extracellular matrix dependent metalloproteinases, plays an important role in tissue invasion and metastasis.
The EDTA in the dressing removes zinc to inhibit the activity of matrix metalloproteinases (MMP), thus creating a suitable environment for wound healing.
1 The production of inflammatory and pro-inflammatory mediators2 and matrix metalloproteinases (MMPs)3 are increased during exercise activity.
The dentin becomes increasingly exposed in advanced stages and exposes the organic matrix to breakdown by host-derived enzymes, such as matrix metalloproteinases (MMPs) present in dentin and saliva.
This event is mediated by the action of matrix metalloproteinases (MMPs), a family of [Zn.
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