methotrexate

meth·o·trex·ate  (mth-trkst)

n.

A toxic antimetabolite, C₂₀H₂₂N₈O₅, that acts as a folic acid antagonist to interfere with cellular reproduction and is used in the treatment of psoriasis, certain cancers, and certain inflammatory diseases such as rheumatoid arthritis.

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[methotre- (probably shortening and alteration of methylaminopterin, one of its chemical names : methyl + aminopterin) + perhaps (o)x(y)- + -ate².]

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methotrexate  (mth-trkst)

A toxic drug that acts as a folic acid antagonist to interfere with cellular reproduction and is used in the treatment of psoriasis, certain cancers, and certain inflammatory diseases, such as rheumatoid arthritis. Chemical formula: C₂₀H₂₂N₈O₅.

Thesaurus

Noun

1.

methotrexate - toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis amethopterin, methotrexate sodium antimetabolite - an antineoplastic drug that inhibits the utilization of a metabolite immune suppressant drug, immunosuppressant, immunosuppressive, immunosuppressive drug, immunosuppressor - a drug that lowers the body's normal immune response