microsome

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mi·cro·some

 (mī′krə-sōm′)
n.
A small particle in the cytoplasm of a cell, typically consisting of fragmented endoplasmic reticulum to which ribosomes are attached.

mi′cro·so′mal (-sō′məl), mi′cro·so′mic (-sō′mĭk) adj.

microsome

(ˈmaɪkrəʊˌsəʊm)
n
(Biology) any of the small particles consisting of ribosomes and fragments of attached endoplasmic reticulum that can be isolated from cells by centrifugal action
ˌmicroˈsomal adj

mi•cro•some

(ˈmaɪ krəˌsoʊm)

n.
a small vesicle containing fragments of ribosomes and other organelles, formed during cell breakage by centrifugation.
[1880–85]
mi`cro•so′mal, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.microsome - a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNAmicrosome - a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA
cytol, cytoplasm - the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism
granule - a tiny grain
Translations

mi·cro·some

n. microsoma, elemento fino granular del protoplasma.
References in periodicals archive ?
Lonza Walkersville announced its new offering of Silensomes Human Liver Microsomes (HLM) products pooled human liver microsomes for in vitro cytochrome P450 (CYP) phenotyping.
Studies are most frequently performed with (cryopreserved) primary cells or tissue fractions, such as microsomes, S9 or cytosol, derived from animal organs or human donors (Soars et al.
13) showed that ritonavir is metabolized by CYP 3A4 and CYP 3A5 at the same ratio, but indinavir is metabolized by CYP 3A4 than CYP 3A5 in human intestinal microsomes and expressed CYP 3A4/3A5.
1,2,4,5] AIH is divided into two types: Type 1 AIH is characterized by circulating antibodies to nuclei (ANA) or smooth muscle (ASMA) and Type 2 AIH is characterized by the presence of antibodies to liver or kidney microsomes (ALKM-1) and/or to a liver cytosol antigen (ALC-1).
On stipulated day the animals were slaughtered, their livers taken out and microsomes prepared for the estimation of activities of various membrane bound DME such as cytochrome P450 (CP), cytochrome b5 (CB), cytochrome-c-reductase (CCR), aniline hydroxylase (AH), acetanilide hydroxylase (AAH), benzphetamine demethylase (BD), aminopyrine demethylase (APD), N.
A study describing testosterone metabolism in vitro using fresh and frozen pigskin as well as human skin microsomes was published in 2014.
Homogenization of liver samples and isolation of local microsomes were done as described by Nordlie and Arion [24].
Examples of protective and antioxidant properties of 1,4-dihydropyridine derivatives have been provided in a number of recent in vitro studies on low density lipoproteins, mitochondria, microsomes, isolated cells, and cell cultures.
Several studies found an inhibitory effect of [alpha]-naphthoflavone, ketoconazole, troglitazone, tranylcypromine, ebastine, and terfenadine on the rate of astemizole O-demethylation in human small intestinal microsomes and recombinant CYP2J2 isoform (Matsumoto et al.
In an in vitro study of Relizen's effect on the isoenzyme CYP2D6 in pooled human liver microsomes, Dr.