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A synthetic steroid, C29H35NO2, that blocks the action of progesterone and is used in combination with misoprostol to induce abortion in early pregnancy. Also called RU 486.

[(a)mi(no) + alteration of phe(nyl) + pr(opyl) + alteration of est(radiol) + -one.]


(Pharmacology) an antiprogestogenic steroid, used in the medical termination of pregnancy. Formula: C29H35NO2
[C20: from aminophenol + propyne + oestradiol + -one]


(ˌmɪf əˈprɪs toʊn)
an antigestational drug that prevents a fertilized egg from attaching to the uterine wall by blocking the action of progesterone.
[1985–90; probably alter. of (a)mi(no)phe(nol) + pr(opyl) + est(radiol) + -one]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mifepristone - an abortion-inducing drug (trade name RU_486) developed in Francemifepristone - an abortion-inducing drug (trade name RU_486) developed in France; when taken during the first five weeks of pregnancy it blocks the action of progesterone so that the uterus sloughs off the embryo
aborticide, abortifacient, abortion-inducing drug - a drug (or other chemical agent) that causes abortion


n mifepristona
References in periodicals archive ?
The Belfast woman, who cannot be named to protect her daughter's identity, is accused of procuring Mifepristone and Misoprostol, knowing it was to be used with the intention of securing a miscarriage.
One of Planned Parenthood large affiliates has just published a study that they assert shows that the abortion drugs mifepristone (RU-486) and misoprostol can be used safely and effectively following a different protocol than the one laid out by the U.
In the United States, the Food and Drug Administration (FDA) has approved the specific combination of mifepristone and misoprostol for medication abortion, and it is also approved for use in about 50 other countries around the world.
The medications which are widely used are methotrexate, mifepristone and misoprostol [5].
Steinauer of the university Two states - Arizona and Ohio - require that the FDA-approved regimen be used when prescribing the progesterone antagonist mifepristone for abortion, according to the Guttmacher Institute, which seeks to advance reproductive rights.
In the case of mifepristone and levonorgestrel emergency contraception (Plan B), the agency's mechanisms were used to impede and stall, rather than facilitate, availability.
METHODS: At 10 facilities in Bangladesh, 651 consenting women who were seeking menstrual regulation services and who were 63 days or less past their last menstrual period received 200 mg of mifepristone followed 24 hours later by 800 mcg of buccal misoprostol, administered either at home or in the clinic.
We found countless websites selling abortion drugs including Misoprostol and Mifepristone.
The recommended method of medical abortion up to 9 weeks of pregnancy is 200 mg mifepristone orally followed 24-48 hours later by 800 [micro]g of misoprostol, administered either vaginally, buccally or sublingually.
An Irish Sunday Mirror investigation found 146 killer tablets - mifepristone and misoprostal - were found by officers as they were brought into the country.
The use of mifepristone (Mifeprix) in combination with misoprostol to terminate early pregnancies increased from 161,000 in 2005 to 199,000 in 2008.
1) The women were all 63-90 days pregnant and were given 200 mg of oral mifepristone, followed in 48 hours by 800 mcg of vaginal misoprostol; up to five additional doses of misoprostol (400 mcg each) were administered at three-hour intervals if necessary.