mitochondrial DNA


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Related to mitochondrial DNA: Mitochondrial disease

mitochondrial DNA

n. Abbr. mtDNA
DNA that is contained in the mitochondria of eukaryotic cells and is inherited maternally.

mitochondrial DNA

n
(Genetics) DNA found in mitochondria, which contains some structural genes and is generally inherited only through the female line. Abbreviation: mtDNA
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Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain.
The interpretation of mitochondrial DNA (mtDNA) nucleotide sequencing results in casework is a matter of professional judgement and expertise.
A pioneering study has found that patients with Parkinsons disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death in that area.
Background: Mitochondrial DNA (mtDNA) content measured by different techniques cannot be compared between studies, and age- and tissue-related control values are hardly available.
amp;nbsp;Unlike nuclear DNA, which is inherited in equal quantities from both parents, the mitochondrial DNA - present outside the nucleus - is inherited only from the mother.
For a "three-parent baby," getting disease-free mitochondrial DNA from a surrogate may do more than just avert disease: For better or for worse, a donor's mitochondria could also affect the course of aging, new research shows.
The team at the Oregon Health & Science University has discovered that induced pluripotent stem, or iPS, cells, a type of stem cell derived from patients' skin or blood cells contain faulty mitochondrial DNA.
Detection of Y chromosome microdeletions and mitochondrial DNA mutations in male infertility patients.
The study showed Gulf War veterans "not only had more mitochondrial DNA, but also more mitochondrial DNA damage than otherwise healthy adults.
The researchers discovered that pre-diabetic people, who were considered to be insulin resistant, also had altered mitochondrial DNA.
An MRT technique that entails removing the mitochondrial DNA from the intended mother's egg is being evaluated at two centers in the United States--the University of Oregon, Eugene, where it has been performed in macaque monkeys, and the New York Stem Cell Foundation.
Children may inherit mitochondrial DNA defects from their mothers, but not their fathers.

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