Down syndrome

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Down syndrome

 (doun) or Down's syndrome (dounz)
n.
A congenital disorder caused by the presence of an extra 21st chromosome and marked usually by moderate to severe intellectual disabilities, short stature, and a flattened facial profile. Also called trisomy 21.

[After John Langdon Haydon Down (1828-1896), British physician.]

Down′

(or Down's′) syn′drome


n.
a genetic disorder associated with the presence of an extra chromosome 21, characterized by mental retardation, weak muscle tone, and epicanthic folds at the eyelids.
Formerly, mongolism. Also called trisomy 21.
[1960–65; after John Latin. H. Down (1828–96), British physician]

Down syndrome

A congenital disorder caused by the presence of an extra 21st chromosome. People with Down syndrome have mild to moderate mental retardation, short stature, and a flattened facial profile.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Down syndrome - a congenital disorder caused by having an extra 21st chromosomeDown syndrome - a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation
trisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell
Translations
síndrome de Down
Downin oireyhtymäDownin syndroomamongolismimongoloidismi
syndrome de Down
sindrom Down
ダウン症
downsyndroommongolismesyndroom van Down
Downs syndrom

Down syn·drome

[MIM*190685]
n. síndrome de Down, anormalidad citogenética del cromosoma 21 caracterizada por retraso mental y facciones mongoloides.
References in periodicals archive ?
Most reprehensible is his dismissal of Adam as a Mongoloid idiot on whom attention is wasted.