monocytes


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Related to monocytes: Lymphocytes, Basophils, Eosinophils, Neutrophils

monocytes

A type of large white blood cell. See leukocytes.
References in periodicals archive ?
As the researchers observed the same elevated levels of TF-expressing monocytes in nonhuman primates infected with SIV, the monkey form of HIV, they administered Ixolaris to five SIV-infected monkeys.
Leukocyte counts (eosinophils, monocytes, lymphocytes, neutrophils and basophils) were measured in whole blood drawn into 5 ml vacutainer tubes (Becton Dickinson and Company, New Jersey, USA) containing EDTA (40 [micro]L of K3-EDTA, 0.
They include monocytes, which are large white blood cells that can differentiate into scavenger cells macrophages and dendritic cells in response to inflammatory signals.
Smokers demonstrated statistically significantly different percentage of neutrophils, lymphocytes, eosinophils, and monocytes when compared to non-smokers (P < 0.
Chemotaxis assays were performed in modified Boyden chambers separated with three groups: (1) random migration groups: monocytes suspension with DMEM were added to the upper well and DMEM were added to the lower well; (2) chemotaxis groups: monocytes suspension were added to the upper well and supernatants of 3T3-L1 adipocytes incubated with oxLDL for 12 h or different concentrations of L-4F (1, 10, and 50 [micro]g/ml) were added to the lower well; and (3) positive control group: monocytes suspension were added to the upper well, and active serum was added to the lower well.
U937 monocytes at a concentration of 3 x 106 cells per ml were fluorescently labeled with 2 [micro]M of BCECF-AM in RPMI-1640 medium for 45 min at 37[degrees]C and 5% C[O.
Another receptor frequently used for antigen targeting is the "mannose receptor" (MR/CD206), a C-type lectin receptor (CLR) not expressed on monocytes but highly expressed on DCs.
For protein analyses by Western blotting monocytes were lysed in homogenization buffer (containing 50 mmol/L Tris-HCl, pH 8; 100 mmol/L NaCl, 100 mmol/L [beta]-mercaptoethanol, 50 mmol/L NaF, 2 mmol/L ethylenediaminetetraacetic acid, and complete mini protease inhibitor cocktail (Roche Diagnostics; Germany)); proteins were separated by 12.
The researchers believe that the newly arrived monocytes could worsen tissue damage because they may exacerbate ongoing or underlying inflammation, but this aspect is still under study.
Phenotypic and Functional Heterogeneity of Monocytes and Macrophages
Prior to currently acknowledged division of monocyte population into classical CD14++CD16-, non-classical CD14+CD16++ and intermediate CD14++CD16+ cells, monocytes have been divided to CD16-negative (referred to as CD14+CD16- or CD14highCD16low) and CD16-positive (referred to as CD14lowCD16+ or CD14lowCD16high) monocytes [5-7].
The result of this study showed that there is negative association of smoking with blood pressure and monocytes while leucocyte count and eosinophil counts was increased in smokers.

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