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NRTI

   Also found in: Medical, Acronyms 0.01 sec.
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Noun1.NRTI - an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs
AZT, Retrovir, ZDV, zidovudine - an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrow
drug cocktail, HAART, highly active antiretroviral therapy - a combination of protease inhibitors taken with reverse transcriptase inhibitors; used in treating AIDS and HIV
3TC, lamivudine - a nucleoside reverse transcriptase inhibitor that is very effective in combination with zidovudine in treating AIDS and HIV
reverse transcriptase inhibitor - an antiviral drug that inhibits the action of reverse transcriptase in retroviruses such as HIV


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Two of these studies were conducted in clinically advanced, three-class antiretroviral (NNRT, NRTI, PI) treatment-experienced adults and one was conducted in treatment-naE[macron]ve adults.
The GI and CNS adverse effects of the twice daily NRTI combination of zidovudine and lamivudine, as well as their associations with lipoatrophy and anemia, make them a less desirable choice.
24-Week data from Study AVX201: a prospective, randomized, double-blind, dose-ranging phase IIb study of apricitabine in treatment-experienced patients with M184Vand NRTI resistance.
 
 
 
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