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v. stained, stain·ing, stains
1. To discolor, soil, or spot: The spilled juice stained the carpet.
2. To bring into disrepute; taint or tarnish: The scandal stained the mayor's reputation.
3. To change the color of (a piece of wood, for example) by applying a stain.
4. To treat (a specimen for the microscope) with a reagent or dye in order to identify cell or tissue structures or microorganisms.
To produce or receive discolorations: upholstery that stains easily.
1. A discolored or soiled spot or smudge: a stain that was difficult to scrub out.
2. A diminishment of one's moral character or good reputation by being associated with something disgraceful.
3. A liquid substance applied especially to wood that penetrates the surface and imparts a rich color.
4. A reagent or dye used for staining microscopic specimens.

[Middle English steinen, partly from Old French desteindre, desteign-, to deprive of color (des-, dis- + teindre, to dye, from Latin tingere), and partly from Old Norse steina, to paint.]

stain′a·ble adj.
stain′er n.
Synonyms: stain, blot1, brand, stigma, taint
These nouns denote a mark of discredit or disgrace, as on one's good name: a stain on his honor; a blot on an otherwise clean police record; the brand of cowardice; the stigma of ignominious defeat; the taint of political corruption.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.staining - (histology) the use of a dye to color specimens for microscopic study
dyeing - the use of dye to change the color of something permanently
Gram method, Gram stain, Gram's method, Gram's procedure, Gram's stain - a staining technique used to classify bacteria; bacteria are stained with gentian violet and then treated with Gram's solution; after being decolorized with alcohol and treated with safranine and washed in water, those that retain the gentian violet are Gram-positive and those that do not retain it are Gram-negative
histology - the branch of biology that studies the microscopic structure of animal or plant tissues
2.staining - the act of spotting or staining somethingstaining - the act of spotting or staining something
dirtying, soiling, soilure - the act of soiling something


(= change in colour)(Ver)färbung f; (= soiling)Verschmutzung f
(esp Tech: = dyeing) → Färben nt; (of wood)Beizen nt


n. coloración, tintura.
References in periodicals archive ?
Immunohistochemical stains for basal cells, such as HMWCK or more recently p63 are currently used in the diagnosis of focal prostate cancer but there are limitations in their use as negative staining for basal cell markers is by itself not diagnostic of carcinoma and also due to technical reasons these stains may be falsely positive thus it is necessary to interpret negative staining in an atypical focus in light of positive staining in adjacent benign glands which is used as an internal positive control.
Ultrastructure of Berlin squirrelpox virus particles from skin lesions on a red squirrel in Berlin, Germany, visualized by negative staining (uranyl acetate) (original magnification x68,000).
In one of our studies, (171) reduced immunoreactivity, instead of completely negative staining, was observed in suspicious cells in one-half of malignant cases.
1) reported very weak or negative staining for p53 in benign leiomyomas with no p53 mutation and a strong positive correlation between p53 staining and p53 mutation in LMSs.
From practical viewpoint, the most helpful immuno-histochemical findings are the negative staining of sex cord tumours for epithelial membrane antigen, and positive staining for Inhibin and Calretinin.
9,10,11,12] The negative staining for EMA, WT1, CD15 [13] and CK7 [14] also helps.
Immunohistochemistry showed positive staining for S-100 protein, Vimentin, smooth muscle actin (SMA) and negative staining for estrogen and progesterone.
Additional immunostains performed at our institution revealed negative staining of the lesional cells for wide spectrum cytokeratin (CK), CK OSCAR (Figure 5A), epithelial membrane antigen (EMA), S100, HMB-45, smooth muscle actin and positive staining for CD34, desmin (Figure 5 B), estrogen receptor (Figure 6), and BCL-2.
12 [micro]l of the dilutions were allowed to adsorb on carbon coated copper grid for 1 min followed by negative staining with aqueous uranyl acetate (0.
The positive staining for TTF- 1, thyroglobulin, and negative staining for ER, PR, GCDFP-15, GATA3 ruled out primary breast papillary carcinoma, papilloma and tubular carcinoma.
Very recently, we have reported the reversible negative staining with imidazole and zinc salts of LPS aggregates separated in agarose gels [37].