Over 500 products have been investigated for neuroprotective
effects including those from the categories of free radical scavengers, anti-excitotoxic agents, apoptosis (programmed cell death) inhibitors, anti-inflammatory agents, neurotrophic factors, metal ion chelators, ion channel modulators and gene therapy.
Their work, published this month in Neurology, may suggest a neuroprotective
target for drug discovery efforts.
effects of inhaled lavender oil on scopolamine-induced dementia via anti-oxidative activities in rats.
We investigated the neuroprotective
effects of CoQ10 against Amyloid beta(25-35) (A[beta](25-35))-induced neurotoxicity in rat cortical neurons.
Mice with a condition that serves as a laboratory model for Down syndrome perform better on memory and learning tasks as adults if they were treated before birth with neuroprotective
peptides, according to researchers at the National Institutes of Health.
Keywords: Corpus officinalis Iridoid glycoside 7-0-Butylmorroniside HT22 Neuroprotective
The research has turned up clues to a neuroprotective
mechanism that could lead to a treatment for Alzheimer's disease.
International Conference on Neuroprotective
Agents (8th: 2006: Mackinac Island, MI) Ed.
The studies, published 6 September 2005 in Current Biology, suggest that normally "DJ-1 has a neuroprotective
role against different oxidative stimuli," says Darren Moore, an instructor in neurology at the Johns Hopkins University School of Medicine who has studied the gene.
This magnesium might be neuroprotective
so it might help patients who are experiencing potential neurological injury due to the fact that the nerves, the neurons are not getting enough oxygen,'' said Dr.
Early detection of the cognitive declines that presage Alzheimer's disease would be useful because the neuroprotective
drugs now avail able work best when administered early in the course of disease, says neuroscientist Zhong-Lin Lu of the University of Southern California in Los Angeles, another collaborator on the study.
drugs are mostly still in clinical trials.