Niemann-Pick disease


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Related to Niemann-Pick disease: Tay-Sachs disease, Gaucher disease

Nie·mann-Pick disease

 (nē′mən-pĭk′)
n.
An inherited disorder of lipid metabolism characterized by the accumulation of lipids in the spleen and liver and sometimes in the lungs, bone marrow, and brain. It is divided into several types, one of which occurs chiefly in infants of eastern European Jewish descent.

[After Albert Niemann (1880-1921), German pediatrician, and Ludwig Pick (1868-1944), German pathologist.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Niemann-Pick disease - a disorder of lipid metabolism that is inherited as an autosomal recessive trait
inborn error of metabolism - any of a number of diseases in which an inherited defect (usually a missing or inadequate enzyme) results in an abnormality of metabolism
autosomal recessive defect, autosomal recessive disease - a disease caused by the presence of two recessive mutant genes on an autosome
lipidosis - a disorder of lipid metabolism; abnormal levels of certain fats accumulate in the body
References in periodicals archive ?
Moreover, Niemann-Pick disease can show myelin-like figures, but they are absent from mesangial cells and arterial cells contrary to Fabry disease.
Niemann-Pick disease is a rare and fatal disorder of the central nervous system (the brain and spinal cord) that has no cure.
corpus callosum DTI and volume measures are associated with disease severity in pediatric Niemann-Pick disease Type c1.
Thus, keeping in view the clinical history, peripheral blood and bone marrow findings, results of special stains, the diagnosis of Niemann-pick disease type B was suspected.
The grant will fund an interactive learning experience for children affected by Niemann-Pick diseases, through fun and sensory learning and play using the latest technology in multi-purpose computer tablets and learning apps.
She is running her first marathon to raise money for the Niemann-Pick Disease Group (UK).
Leah has Niemann-Pick disease, a genetic illness that causes memory loss similar to Alzheimer's.
There are only 500 children in the world suffering from Niemann-Pick disease, which will eventually claim the youngster's life.
The diagnosis of Niemann-Pick disease was confirmed via measurement of lysosomal sphingomyelinase (0.
Leah is one of 500 children around the world suffering from Niemann-Pick disease.
Leah is one of 500 young children around the world suffering from Niemann-Pick disease, which will eventually claim her life.