nifurtimox


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Related to nifurtimox: Eflornithine
Translations

nifurtimox

n nifurtimox m
References in periodicals archive ?
Currently, there are only two treatments for Chagas disease available: nifurtimox and benznidazole.
Only two drugs (Benznidazol, Bz and Nifurtimox, Nx) are currently accepted for treatment, however they cause severe adverse effects and their efficacy is still controversial.
A combination of nifurtimox and eflornithine has shown promising results in the treatment of second stage of African trypanosomiasis (18), but its use is marred by dangerous side-effects.
For instance, there are drugs to treat Chagas disease, like benznidazole and nifurtimox, but they are hard to procure, often not effective in adults after the symptoms of heart disease begin and so toxic they cannot be taken by pregnant women.
The current treatments for this disease are the synthetic drugs nifurtimox and benzonidazol, which are highly toxic.
Bayer will double its existing donation of nifurtimox to treat Chagas disease.
Using the same arguments as Roche, Bayer, which makes Nifurtimox, the second medicine proven effective against Chagas, stopped producing the drug at almost the same time.
14) extraction Metronidazole (anti-inflammatory more than antihelmintic) Wound care Cutaneous Praziquantel 40 schistosomiasis mg/kg/day stat Sometimes repeated Systemic steroids in Katayama fever Avoidance of water in endemic areas Snail control Trypanosomiasis Nifurtimox (with gamma interferon Suramin, pentamidine Eflornithine WHO control measures Filarial Ivermectin elephantiasis Adjunctive albendazole, doxycycline Surgical correction DEC = diethylcarbamazine; ANS = autonomic nervous system; GIT = gastrointestinal; CVS = cardiovascular system; CSF = cerebrospinal fluid; PCR = polymerase chain reaction.
No vaccine is available and treatment in the acute phase consists of Nifurtimox or Benznidazole (not available in the US).
The currently available drugs, Nifurtimox and Benznidazole, have serious side effects and cannot treat the chronic phase (19).
If caught early, strong anti-protozoal drugs such as nifurtimox can bring the parasite to undetectable levels or, in some cases, eliminate it entirely.
Nifurtimox, a drug used to treat Chagas disease, may be effective, but has not yet been validated for use.