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Related to Nociceptive neuron: Nocireceptors


A sensory receptor that responds to pain.

[Latin nocēre, to hurt; see nocent + (re)ceptor.]
References in periodicals archive ?
Recently, we have introduced a way to target the delivery of sodium channel blockers selectively to nociceptive neurons, and thus capitalize on their effectiveness in blocking action potentials but now only at sites of pain generation.
One plausible explanation is that nerve injury induces a spontaneous discharge in sensory neurons releasing MMP-9 and pro-IL-1[beta] into the extracellular matrix, where MMP-9 cleaves pro-IL-1 p to IL-1[beta], which promotes hyperexcitability in adjacent nociceptive neurons (16).
The excitatory amino acid glutamate is the major excitatory neurotransmitter released at the central terminals of primary afferent nociceptive neurons after noxious stimulation (Bridges et al.
Conventional wisdom was that the nociceptive neurons in the skin can't tell the difference between heat and mechanical pain, like a pin prick.
Nociceptive processing after SCI is apparently more complicated; inhibition of below-level spinal nociceptive neurons by 5-HT has been found to be reversed by both 5-HT1A and 5-HT3 antagonists [57], but spinal 5-HT3 receptors have also been shown to facilitate at-level allodynia after SCI [58-59].