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Norvir

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Noun1.Norvir - a protease inhibitor (trade name Norvir) used in treating HIV
protease inhibitor, PI - an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs


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Patients received either 20 mg, 50 mg, or 125 mg of elvitegravir with 100 mg of Norvir or Norvir boosted by a protease inhibitor (either Aptivus [tiptranavir] or Prezista).
December 2, 2003 (the day alter World AIDS Day): Abbott Laboratories raises the price of Norvir by more than 400% and ensures that its own boosted product, Kaletra, becomes the cheapest boosted PI on the market.
But the company's random-ized crossover trial in 48 HIV-negative volunteers who took Lexiva for two weeks with Nexium, and later for two weeks without, found that this did not happen, at least with the 20 mg dose of Nexium tested (the drug is supplied in 20 and 40 mg doses)--whether or not the Lexiva was "boosted" with a small dose of Norvir.
 
 
 
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